|Venue: Allianz Park Date: Saturday, 21 December Kick-off: 15:00 GMT Coverage: BBC local radio and the BBC Sport website|
Maro Itoje returns for Saracens after missing the win over Munster last week.
Ben Spencer starts at scrum-half, Brad Barritt returns at centre and Wales prop Rhys Carre is set to make his Premiership debut from the bench.
Bristol welcome back full-back Charles Piutau, who is one of six changes.
Backs Luke Morahan and Andy Uren get starts while prop John Afoa is back from a dead leg and is joined by Harry Thacker and captain Steven Luatua.
Bristol lie in second place, two points behind leaders Northampton, while champions Saracens – deducted 35 points for breaching salary cap rules – are 14 points adrift of 11th-placed Leicester.
Saracens: Malins; Maitland, Tompkins, Barritt (capt), Daly; Farrell, Spencer; Vunipola, George, Koch, Itoje, Kruis, Isiekwe, Earl, Vunipola.
Replacements: Singleton, Carre, Lamositele, Skelton, Wray, Wigglesworth, Taylor, Lewington.
Bristol: Piutau; Morahan, O’Conor, Bedlow, Fricker; Sheedy, Uren; Woolmore, Thacker, Afoa, Joyce, Vui, Luatua (capt), Heenan, Hughes.
Replacements: Capon, Lay, Lahiff, Holmes, Hamilton, Randall, Lloyd, Leiua.